Article
Association Study of GWAS-Derived Loci with Height in Brazilian Children: Importance of MAP3K3, MMP24 and IGF1R Polymorphisms for Height Variation.
Hormone research in paediatrics - 1 Jan 2015
Fontenele Eveline Gadelha Pereira, Moraes Maria Elisabete Amaral de, d'Alva Catarina Brasil, Pinheiro Daniel Pascoalino, Landim Sara Aguiar Sales Pinheiro, Barros Fernando Antonio de Sousa, Trarbach Ericka Barbosa, Mendonca Berenice Bilharinho de, Jorge Alexander Augusto Lima
Abstract excerpt
BACKGROUND/AIM: The single nucleotide polymorphisms (SNPs) rs2282978 (CDK6), rs2425019 (MMP24), rs8081612 (MAP3K3), rs2871865 (IGF1R) and rs3782415 (SOCS2) were among the SNPs most strongly associated with height in a meta-analysis of 47 genome-wide association studies (GWAS) involving 114,223 adults from six ethnic groups. The present study aimed to examine associations between these SNPs and height in Brazilian...
