Article
Genetic approaches to stature, pubertal timing, and other complex traits.
Molecular genetics and metabolism - 1 Jan 2000
Palmert Mark R, Hirschhorn Joel N
Abstract excerpt
The factors that regulate the timing of puberty remain largely elusive, as do the factors that modulate childhood growth and adult height. However, it is clear that these developmental processes are highly heritable--much of the natural variation in growth and timing of puberty is due to genetic variation within the population. In this review, we discuss how recent genetic and genomic advances can be exploited to...
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