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Article

Impact of KRAS mutation on the tumor microenvironment in colorectal cancer.

International journal of biological sciences - 1 Jan 2024

Zhou Yiru, Kuang Yeye, Wang Chan, Yu Yijian, Pan Lijuan, Hu Xiaotong

Abstract excerpt

Kirsten rat sarcoma viral oncogene homolog (KRAS) is an oncogene implicated in the pathophysiology of many cancers. Increasing evidence shows that KRAS mutation is correlated with poor prognosis in numerous cancers, including colorectal cancer (CRC), breast cancer, and melanoma. KRAS also participates in regulating the CRC microenvironment. However, the direct and indirect therapeutic targets of KRAS in CRC have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38481800
DOI: 10.7150/ijbs.88779
PMCID: PMC10929194

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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