Article
The pseudoentropy of allele frequency trajectories, the persistence of variation, and the effective population size.
Bio Systems - 1 Apr 2024
Vellnow Nikolas, Gossmann Toni I, Waxman David
Abstract excerpt
To concisely describe how genetic variation, at individual loci or across whole genomes, changes over time, and to follow transitory allelic changes, we introduce a quantity related to entropy, that we term pseudoentropy. This quantity emerges in a diffusion analysis of the mean time a mutation segregates in a population. For a neutral locus with an arbitrary number of alleles, the mean time of segregation is...
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