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Article

A numerical framework for genetic hitchhiking in populations of variable size.

Genetics - 3 Mar 2022

Friedlander Eric, Steinrücken Matthias

Abstract excerpt

Natural selection on beneficial or deleterious alleles results in an increase or decrease, respectively, of their frequency within the population. Due to chromosomal linkage, the dynamics of the selected site affect the genetic variation at nearby neutral loci in a process commonly referred to as genetic hitchhiking. Changes in population size, however, can yield patterns in genomic data that mimic the effects of...

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Identifiers

PMID: 35143667
DOI: 10.1093/genetics/iyac012
PMCID: PMC8893261

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