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Article

Allelic Entropy and Times until Loss or Fixation of Neutral Polymorphisms.

Genes - 2 Sept 2023

Ferretti Luca, Ribeca Paolo

Abstract excerpt

In the diffusion approximation of the neutral Wright-Fisher model, the expected time until fixation or loss of a neutral allele is proportional to the initial entropy of the distribution of the allele in the population. No explanation is known for this coincidence. In this paper, we show that the rate of entropy dissipation is proportional to the number of segregating alleles. Since the final fixed state has zero...

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Identifiers

PMID: 37761891
DOI: 10.3390/genes14091751
PMCID: PMC10530898

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