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Article

Accumulation and maintenance of information in evolution.

Proceedings of the National Academy of Sciences of the United States of America - 6 Sept 2022

Hledík Michal, Barton Nick, Tkačik Gašper

Abstract excerpt

Selection accumulates information in the genome-it guides stochastically evolving populations toward states (genotype frequencies) that would be unlikely under neutrality. This can be quantified as the Kullback-Leibler (KL) divergence between the actual distribution of genotype frequencies and the corresponding neutral distribution. First, we show that this population-level information sets an upper bound on the...

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Identifiers

PMID: 36037343
DOI: 10.1073/pnas.2123152119
PMCID: PMC9457054

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