Article
Selective sweeps in multilocus models of quantitative traits.
Genetics - 1 Sept 2012
Pavlidis Pavlos, Metzler Dirk, Stephan Wolfgang
Abstract excerpt
We study the trajectory of an allele that affects a polygenic trait selected toward a phenotypic optimum. Furthermore, conditioning on this trajectory we analyze the effect of the selected mutation on linked neutral variation. We examine the well-characterized two-locus two-allele model but we also provide results for diallelic models with up to eight loci. First, when the optimum phenotype is that of the double...
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