Article
Associations between cytokines and the risk of female and male infertility: A two-sample Mendelian randomization analysis.
Journal of reproductive immunology - 1 Jun 2024
Zhang Lei, Li Honglin, Wu Zhijuan, Han Letian, Zhang Jianwei
Abstract excerpt
PURPOSE: Observational studies have linked cytokines to the occurrence of female and male infertility. However, it is not clear how biomarkers of inflammation are causally related to infertility. To explore whether genetic variants in circulating cytokines are associated with the pathogenesis of infertility, we performed two-sample Mendelian randomization (MR) analysis. METHODS: A total of 31,112 individuals of...
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