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Article

Exploring the genetic association between inflammatory cytokines and primary ovarian insufficiency: A Mendelian randomization study.

Cytokine - 1 Jun 2025

Wu Jie, Fu Yancheng, Qiu Zhengqi

Abstract excerpt

PURPOSE: This study aims to investigate the genetic underpinnings of Primary Ovarian Insufficiency (POI) by examining the association between 91 inflammatory cytokines identified through genome-wide association studies (GWAS) and POI, using Mendelian randomization (MR) to explore potential causal relationships. METHODS: We utilized Mendelian Randomization (MR) to investigate the causative links between...

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Identifiers

PMID: 40184912
DOI: 10.1016/j.cyto.2025.156937

Genes

CCL19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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