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Article

The causal relationship between serum metabolites and the development of infertility: A Mendelian randomization analysis.

Medicine - 7 Aug 2026

Zhang Yinuo, Ma Sicheng, Wang Tingyu, Hu Jing, Gao Yizhe, Yu Wenlin, Liu Wenbang, Wang Yifei, Zhang Chenming, Sun Zixue

Abstract excerpt

Infertility is a complex and sensitive phenomenon experienced by many couples worldwide. Our study investigated the causal effects of 486 serum metabolites on infertility using a Mendelian randomization (MR) approach, providing insights into the etiology of infertility and available treatments. Genetic data for these serum metabolites were obtained from the Metabolomics genome-wide association study server....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42566588
DOI: 10.1097/MD.0000000000049674
PMCID: PMC13456910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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