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Article

Genetic insights into the immunological basis of male infertility: a translational perspective.

F&S science - 1 May 2025

Wang Yi, Hong Yanggang

Abstract excerpt

OBJECTIVE: To elaborate the causal relationships between specific immunocyte phenotypes and male infertility. DESIGN: Mendelian randomization using genome-wide association study data. SUBJECTS: Large cohorts of European ancestry. EXPOSURE: 731 immunocyte phenotypes or male infertility. MAIN OUTCOMES MEASURES: Genetic variants were used as instrumental variables to infer causality, minimizing confounding and bias....

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Identifiers

PMID: 39988235
DOI: 10.1016/j.xfss.2025.02.002

Genes

CD14
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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