Article
Sporadic deficient mismatch repair in colorectal cancer increases the risk for non-colorectal malignancy: A European multicenter cohort study.
Journal of surgical oncology - 1 Jun 2024
Gkekas Ioannis, Jan Novotny, Kaprio Tuomas, Beilmann-Lehtonen Ines, Fabian Pavel, Tavelin Björn, Böckelman Camilla, Edin Sofia, Strigård Karin, Svoboda Tomas, Hagström Jaana, Barsova Lucie, Jirasek Tomas, Haglund Caj, Palmqvist Richard, Gunnarsson Ulf
Abstract excerpt
BACKGROUND AND OBJECTIVES: Disparities between tumors arising via different sporadic carcinogenetic pathways have not been studied systematically. This retrospective multicenter cohort study evaluated the differences in the risk for non-colorectal malignancy between sporadic colorectal cancer (CRC) patients from different DNA mismatch repair status. METHODS: A retrospective European multicenter cohort study...
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