Article
Small noncoding RNA GcvB is a novel regulator of acid resistance in Escherichia coli.
BMC genomics - 20 Apr 2009
Jin Ye, Watt Rory M, Danchin Antoine, Huang Jian-dong
Abstract excerpt
BACKGROUND: The low pH environment of the human stomach is lethal for most microorganisms; but not Escherichia coli, which can tolerate extreme acid stress. Acid resistance in E. coli is hierarchically controlled by numerous regulators among which are small noncoding RNAs (sncRNA). RESULTS: In this study, we individually deleted seventy-nine sncRNA genes from the E. coli K12-MG1655 chromosome, and established a...
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