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Article

Gene-gene interaction network analysis indicates CNTN2 is a candidate gene for idiopathic generalized epilepsy.

Neurogenetics - 1 Apr 2024

Lin Zhi-Jian, He Jun-Wei, Zhu Sheng-Yin, Xue Li-Hong, Zheng Jian-Feng, Zheng Li-Qin, Huang Bi-Xia, Chen Guo-Zhang, Lin Peng-Xing

Abstract excerpt

Twin and family studies have established the genetic contribution to idiopathic generalized epilepsy (IGE). The genetic architecture of IGE is generally complex and heterogeneous, and the majority of the genetic burden in IGE remains unsolved. We hypothesize that gene-gene interactions contribute to the complex inheritance of IGE. CNTN2 (OMIM* 615,400) variants have been identified in cases with familial adult...

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PMID: 38460076
DOI: 10.1007/s10048-024-00748-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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