Article
Shared genetic architecture between periodontal disease and type 2 diabetes: a large scale genome-wide cross-trait analysis.
Endocrine - 1 Aug 2024
Wu Kevin Chun Hei, Liu Lin, Xu Aimin, Chan Yap Hang, Cheung Bernard Man Yung
Abstract excerpt
PURPOSE: To investigate the relationship between abnormal glucose metabolism, type 2 diabetes (T2D), and periodontal disease (PER) independent of Body Mass Index (BMI), we employed a genome-wide cross-trait approach to clarify the association. METHODS: Our study utilized the most extensive genome-wide association studies conducted for populations of European ancestry, including PER, T2D, fasting glucose, fasting...
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