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The role of latency reversal in HIV cure strategies

27 Aug 2022

Abstract excerpt

One strategy to eliminate latently infected cells that persist in people with HIV on antiretroviral therapy is to activate virus transcription and virus production to induce virus or immune-mediated cell death. This is called latency reversal. Despite clear activity of multiple latency reversal agents in vitro, clinical trials of latency-reversing agents have not shown significant reduction in latently infected...

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PMID: 36029233
DOI: 10.1111/jmp.12613

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