Article
Interferon Regulatory Factor 5 Gene Polymorphisms and mRNA Expression Levels Are Associated with Neuromyelitis Optica Spectrum Disorder.
Molecular neurobiology - 1 Oct 2024
Wang Gaoning, Jing Liu, Wang Ying, Mehmood Arshad, Zhang Huining, Guo Ruoyi, Zhang Lu, Li Bin
Abstract excerpt
Interferon regulatory factor 5 (IRF5) is a critical transcription factor in the toll-like receptor signaling pathway. It is associated with autoimmune disorders, such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease. However, the relationship between the functional single nucleotide polymorphisms (SNPs) of IRF5 and its mRNA expression level in patients with neuromyelitis...
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