Article
STAT4 Polymorphisms are Associated with Neuromyelitis Optica Spectrum Disorders.
Neuromolecular medicine - 1 Dec 2017
Shi Ziyan, Zhang Qin, Chen Hongxi, Lian Zhiyun, Liu Ju, Feng Huiru, Miao Xiaohui, Du Qin, Zhou Hongyu
Abstract excerpt
STAT4 plays a crucial role in the functioning of the innate and adaptive immune cells and has been identified as a susceptibility gene in numerous autoimmune disorders. However, its association with neuromyelitis optica spectrum disorders (NMOSD) remains uncertain. Here, we performed a case-control study to determine whether STAT4 contributed to the risk of NMOSD. We tested five STAT4 SNPs in 233 patients with...
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