Article
Strain background of Candida albicans interacts with SIR2 to alter phenotypic switching.
Microbiology (Reading, England) - 1 Mar 2024
Woodruff Andrew L, Berman Judith, Anderson Matthew
Abstract excerpt
The genetic background between strains of a single species and within a single strain lineage can significantly impact the expression of biological traits. This genetic variation may also reshape epigenetic mechanisms of cell identity and environmental responses that are controlled by interconnected transcriptional networks and chromatin-modifying enzymes. Histone deacetylases, including sirtuins, are critical...
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