Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low- and High-Grade Glioma-Associated Vascular Cells Differentially Regulate Tumor Growth.

Molecular cancer research : MCR - 2 Jul 2024

Muthukrishnan Sree Deepthi, Qi Haocheng, Wang David, Elahi Lubayna, Pham Amy, Alvarado Alvaro G, Li Tie, Gao Fuying, Kawaguchi Riki, Lai Albert, Kornblum Harley I

Abstract excerpt

A key feature distinguishing high-grade glioma (HG) from low-grade glioma (LG) is the extensive neovascularization and endothelial hyperproliferation. Prior work has shown that tumor-associated vasculature from HG is molecularly and functionally distinct from normal brain vasculature and expresses higher levels of protumorigenic factors that promote glioma growth and progression. However, it remains unclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Glioma

Share to Mutation

Share to Neoplasm Grading

Share to Neovascularization, Pathologic

Source

Open in PubMed Open full text

Identifiers

PMID: 38441553
DOI: 10.1158/1541-7786.MCR-23-1069
PMCID: PMC11217726

Genes

ASPN
GPM6A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low- and High-Grade Glioma-Associated Vascular Cells Differentially Regulate Tumor Growth.PMID 38441553Read ↗

Low- and high-grade glioma endothelial cells differentially regulate tumor growthSemantic proximity Read ↗

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas.Semantic proximity Read ↗

Identification of diverse tumor endothelial cell populations in malignant gliomaSemantic proximity Read ↗

Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastomaSemantic proximity Read ↗

Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low‐grade gliomaSemantic proximity Read ↗

Characteristics of tumor-associated endothelial cells derived from glioblastoma multiformeSemantic proximity Read ↗

Cancer stem cell-vascular endothelial cell interactions in glioblastoma.Semantic proximity Read ↗

Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma.Semantic proximity Read ↗

Vascular Transdifferentiation in the CNS: A Focus on Neural and Glioblastoma Stem‐Like CellsSemantic proximity Read ↗

The glioblastoma vasculature as a target for cancer therapySemantic proximity Read ↗

Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel TreatmentsSemantic proximity Read ↗

Single-cell transcriptomic analysis reveals the functional heterogeneity and clinical signification of pericyte subpopulations in gliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.