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Vascular Transdifferentiation in the CNS: A Focus on Neural and Glioblastoma Stem‐Like Cells

1 Jan 2016

Abstract excerpt

Glioblastomas are devastating and extensively vascularized brain tumors from which glioblastoma stem‐like cells (GSCs) have been isolated by many groups. These cells have a high tumorigenic potential and the capacity to generate heterogeneous phenotypes. There is growing evidence to support the possibility that these cells are derived from the accumulation of mutations in adult neural stem cells (NSCs) as well as...

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PMID: 27738435
DOI: 10.1155/2016/2759403

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