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Article

Immune gene polymorphisms associated with poor response to platelet transfusion and recombinant factor VII administration in Glanzmann thrombasthenia.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2024

Naderi Majid, Mirzaei Ilia, Seidizadeh Omid, Moud Abolfazl Parsi, Sarani Hosna, Avan Amir, Taheri Mohsen, Jahantigh Danial, Keramati Mohammad Reza, Sohrabi Tayebeh

Abstract excerpt

INTRODUCTION: Poor response to platelet and recombinant factor VII administration is a major problem in patients with Glanzmann Thrombasthenia (GT). The risk factors associated with poor response to treatment in these patients are unknown. Some genetic variations of cytokines may contribute to therapy resistance. AIMS: We evaluated, for the first time, whether genetic polymorphisms on cytokine genes are related...

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PMID: 38439143
DOI: 10.1111/hae.14971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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