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Article

Coexistent HCN4 and GATA5 Rare Variants and Atrial Fibrillation in a Large Spanish Family.

The Canadian journal of cardiology - 1 Jul 2024

Fraile Alfonso, Cebrián Jorge, Thuissard-Vasallo Israel, Pérez-Martín Sara, Casado Raquel, Gil-Fournier Belén, Alonso-Martín Joaquín, Tamargo Juan, Caballero Ricardo, Delpón Eva, Cosío Francisco G

Abstract excerpt

BACKGROUND: Familial association of atrial fibrillation (AF) can involve single gene variants related to known arrhythmogenic mechanisms; however, genome-wide association studies often disclose complex genetic variants in familial and nonfamilial AF, making it difficult to relate to known pathogenetic mechanisms. METHODS: The finding of 4 siblings with AF led to studying 47 members of a family. Long-term Holter...

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Source

Identifiers

PMID: 38432398
DOI: 10.1016/j.cjca.2024.02.024

Genes

GATA5
HCN4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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