Article
Identification of rare variants in TNNI3 with atrial fibrillation in a Chinese GeneID population.
Molecular genetics and genomics : MGG - 1 Feb 2016
Wang Chuchu, Wu Manman, Qian Jin, Li Bin, Tu Xin, Xu Chengqi, Li Sisi, Chen Shanshan, Zhao Yuanyuan, Huang Yufeng, Shi Lisong, Cheng Xiang, Liao Yuhua, Chen Qiuyun, Xia Yunlong, Yao Wei, Wu Gang, Cheng Mian, Wang Qing K
Abstract excerpt
Despite advances by genome-wide association studies (GWAS), much of heritability of common human diseases remains missing, a phenomenon referred to as 'missing heritability'. One potential cause for 'missing heritability' is the rare susceptibility variants overlooked by GWAS. Atrial fibrillation (AF) is the most common arrhythmia seen at hospitals and increases risk of stroke by fivefold and doubles risk of...
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