Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rare Truncating HAND2 Variants Predispose to Atrial Fibrillation.

Genes - 17 Jun 2026

Zhang Hong, Hu Xiao-Qing, Li Ning, Zhang Dao-Liang, Qiu Xing-Biao, Yang Chen-Xi, Xu Ying-Jia, Yang Yi-Qing, Wang Juan

Abstract excerpt

Background/Objectives: As the most prevalent supraventricular arrhythmia, affecting around 1% of people worldwide, atrial fibrillation (AF) is implicated with a multitude of detrimental clinical sequelae, encompassing congestive failure, thromboembolic cerebral stroke, and premature death. Accumulating epidemiological evidence convincingly demonstrates genetic defects as a cornerstone in the pathogenesis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Atrial Fibrillation
Share to Basic Helix-Loop-Helix Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GATA4 gene

Share to Genetic Predisposition to Disease

Share to Mutation

Share to Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 42353861
DOI: 10.3390/genes17060701
PMCID: PMC13299968

Genes

HAND2
NPPA
GATA4
HCN4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rare Truncating HAND2 Variants Predispose to Atrial Fibrillation.PMID 42353861Read ↗

Discovery of TBX20 As a Novel Gene Underlying Atrial FibrillationSemantic proximity Read ↗

Genetics and Pharmacogenetics of Atrial FibrillationSemantic proximity Read ↗

Genetics of atrial fibrillation-an update of recent findings.Semantic proximity Read ↗

Atrial fibrillation-a complex polygenetic disease.Semantic proximity Read ↗

Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.Semantic proximity Read ↗

Genetics of Atrial Fibrillation: State of the Art in 2017.Semantic proximity Read ↗

Genetics of atrial fibrillation: from families to genomes.Semantic proximity Read ↗

Genetics of atrial fibrillation.Semantic proximity Read ↗

Atrial fibrillation: the role of common and rare genetic variants.Semantic proximity Read ↗

Genetically based atrial fibrillation: Current considerations for diagnosis and management.Semantic proximity Read ↗

Genetics of Atrial Fibrillation in 2020: GWAS, Genome Sequencing, Polygenic Risk, and Beyond.Semantic proximity Read ↗

Genetically Based Atrial Fibrillation: Current Considerations for Diagnosis and ManagementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.