Article
Pan-azole-resistant Meyerozyma guilliermondii clonal isolates harbouring a double F126L and L505F mutation in Erg11.
Mycoses - 1 Mar 2024
Moreau Jérémy, Noël Thierry, Point Kévin, Tewes Frédéric, Deroche Luc, Clarhaut Jonathan, Fitton-Ouhabi Valérie, Perraud Estelle, Marchand Sandrine, Buyck Julien M, Brunet Kévin
Abstract excerpt
BACKGROUND: Meyerozyma guilliermondii is a yeast species responsible for invasive fungal infections. It has high minimum inhibitory concentrations (MICs) to echinocandins, the first-line treatment of candidemia. In this context, azole antifungal agents are frequently used. However, in recent years, a number of azole-resistant strains have been described. Their mechanisms of resistance are currently poorly...
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