Article
Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae.
mBio - 24 Dec 2019
Kannan Abhilash, Asner Sandra A, Trachsel Emilie, Kelly Steve, Parker Josie, Sanglard Dominique
Abstract excerpt
Multidrug resistance (MDR) has emerged in hospitals due to the use of several agents administered in combination or sequentially to the same individual. We reported earlier MDR in Candida lusitaniae during therapy with amphotericin B (AmB), azoles, and candins. Here, we used comparative genomic approaches between the initial susceptible isolate and 4 other isolates with different MDR profiles. From a total of 18...
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