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Molecular epidemiology and azole resistance mechanism study of Candida guilliermondii from a Chinese surveillance system.

Scientific reports - 19 Apr 2017

Cheng Jing-Wei, Liao Kang, Kudinha Timothy, Yu Shu-Ying, Xiao Meng, Wang He, Kong Fanrong, Xu Ying-Chun

Abstract excerpt

We studied the molecular epidemiology and mechanism of azole resistance of 164 C. guilliermondii isolates from a nationwide multi-center surveillance program. The isolates were identified by ITS gene sequencing, and the in vitro susceptibility to fluconazole and voriconazole was determined by broth microdilution method. The 14-α-demethylase gene ERG11 was amplified and sequenced, and microsatellite analysis was...

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Identifiers

PMID: 28424474
DOI: 10.1038/s41598-017-01106-7
PMCID: PMC5430413

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