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Article

Inferring Alzheimer's Disease Pathologic Traits from Clinical Measures in Living Adults.

Journal of Alzheimer's disease : JAD - 1 Jan 2024

Yang Jingjing, Liu Xizhu, Oveisgharan Shahram, Zammit Andrea R, Nag Sukriti, Bennett David A, Buchman Aron S

Abstract excerpt

Background: Alzheimer's disease neuropathologic changes (AD-NC) are important to identify people with high risk for AD dementia (ADD) and subtyping ADD. Objective: Develop imputation models based on clinical measures to infer AD-NC. Methods: We used penalized generalized linear regression to train imputation models for four AD-NC traits (amyloid-β, tangles, global AD pathology, and pathologic AD) in Rush Memory...

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Identifiers

PMID: 38427476
DOI: 10.3233/JAD-230639
PMCID: PMC11034758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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