Article

Inferring Alzheimer’s disease pathologic traits from clinical measures in living adults

2023-05-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Alzheimer’s disease neuropathologic changes (AD-NC) are important for identify people with high risk for AD dementia (ADD) and subtyping ADD. <h4>Objective</h4> Develop imputation models based on clinical measures to infer AD-NC. <h4>Methods</h4> We used penalized generalized linear regression to train imputation models for four AD-NC traits (amyloid- β , tangles, global AD pa...

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Literature Corpus work: df88e48f-a571-5809-840e-3909cd2200ab
DOI: 10.1101/2023.05.08.23289668

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