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Article

Explainable variational autoencoder (E-VAE) model using genome-wide SNPs to predict dementia.

Journal of biomedical informatics - 1 Dec 2023

Vivek Sithara, Faul Jessica, Thyagarajan Bharat, Guan Weihua

Abstract excerpt

OBJECTIVE: Alzheimer's disease (AD) and AD related dementias (ADRD) are complex multifactorial neurodegenerative diseases. The associations between genetic variants obtained from genome wide association studies (GWAS) are the most widely available and well documented variants associated with ADRD. Application of deep learning methods to analyze large scale GWAS data may be a powerful approach to elucidate the...

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Identifiers

PMID: 37926392
DOI: 10.1016/j.jbi.2023.104536
PMCID: PMC11106718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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