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Article

Causal associations of refractive error and early age-related macular degeneration: A Mendelian randomization study.

Experimental eye research - 1 Apr 2024

Wang Lingling, Wei Wenlong, Zhao YongJi, Chen Sixi, Wu Dongjing, Tu Mengjun

Abstract excerpt

This study aims to determine the risk associated with early age-related macular degeneration (AMD) due to refractive errors (RE) using an analysis of genome-wide association study (GWAS) data through the two-sample Mendelian randomization approach. Single-nucleotide polymorphisms (SNPs) linked to refractive errors (RE) were obtained from numerous GWAS studies involving individuals of European descent. The data...

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PMID: 38423204
DOI: 10.1016/j.exer.2024.109850

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