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Article

Causal association between different types of ametropia and risk of diabetic retinopathy: a two-sample Mendelian randomization study.

BMJ open ophthalmology - 24 Aug 2025

Ma Qian, Yao Hongyan, Wang Sangsang, Chen Jinbo, Shao Yongqing, Zhang Zhe, Wang Tianyu

Abstract excerpt

OBJECTIVE: To investigate the causal link between ametropia and diabetic retinopathy, as well as to offer genetic support for the association between these two conditions. METHODS: This study employed a methodology involving the utilisation of genome-wide association studies data that are publicly accessible. Specifically, single nucleotide polymorphisms (SNPs) that exhibit a strong association with ametropia...

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Topics

Humans
Diabetic Retinopathy
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Risk Factors

Refractive Errors

Genetic Predisposition to Disease

Source

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Identifiers

PMID: 40850694
DOI: 10.1136/bmjophth-2024-001909
PMCID: PMC12410644

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