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Article

Harnessing HetHydrogel: A Universal Platform to Dropletize Single-Cell Multiomics.

Small methods - 1 Jul 2024

Zhou Guoqiang, Li Ting, Du Jingjing, Wu Mengying, Lin Deng, Pu Weilin, Zhang Jingwei, Gu Zhenglong

Abstract excerpt

A universal platform is developed for dropletizing single cell plate-based multiomic assays, consisting of three main pillars: a miniaturized open Heterogeneous Hydrogel reactor (abbreviated HetHydrogel) for multi-step biochemistry, its tunable permeability that allows Tn5 tagmentation, and single cell droplet barcoding. Through optimizing the HetHydrogel manufacturing procedure, the chemical composition, and...

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PMID: 38419597
DOI: 10.1002/smtd.202301631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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