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Article

1D-Reactor Decentralized MDA for Uniform and Accurate Whole Genome Amplification.

Analytical chemistry - 3 Oct 2017

Li Junji, Lu Na, Shi Xulian, Qiao Yi, Chen Liang, Duan Mengqin, Hou Yong, Ge Qinyu, Tao Yuhan, Tu Jing, Lu Zuhong

Abstract excerpt

Multiple displacement amplification (MDA), a most popular isothermal whole genome amplification (WGA) method, suffers the major hurdle of highly uneven amplification, thus, leading to many problems in approaching biological applications related to copy-number assessment. In addition to the optimization of reagents and conditions, complete physical separation of the entire reaction system into numerous tiny...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28853542
DOI: 10.1021/acs.analchem.7b02183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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