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Article

Genetic susceptibility to severe asthma with fungal sensitization.

International journal of immunogenetics - 1 Jun 2017

Overton N L, Simpson A, Bowyer P, Denning D W

Abstract excerpt

Severe asthma is problematic and its pathogenesis poorly understood. Fungal sensitization is common, and many patients with severe asthma with fungal sensitization (SAFS), used to denote this subgroup of asthma, respond to antifungal therapy. We have investigated 325 haplotype-tagging SNPs in 22 candidate genes previously associated with aspergillosis in patients with SAFS, with comparisons in atopic asthmatics...

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Source

Identifiers

PMID: 28371335
DOI: 10.1111/iji.12312

Genes

CCL17
CCL2
MBL2
TLR3
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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