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Article

GEMIN4 Variants: Risk Profiling, Bioinformatics, and Dynamic Simulations Uncover Susceptibility to Bladder Carcinoma.

Archives of medical research - 1 Apr 2024

Mohamed Abdallah S, Salama Afrah F, Sabaa Magdy A, Toraih Eman, Elshazli Rami M

Abstract excerpt

BACKGROUND: The relationship between GEMIN4 genetic variants and cancer, especially bladder carcinoma (BLCA), has been explored without conclusive results. This study aims to elucidate the link between GEMIN4 polymorphisms and BLCA susceptibility through genetic analyses, bioinformatics, and molecular dynamics (MD) simulations. METHODS: A cohort of 249 participants (121 BLCA patients and 128 unrelated controls)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38401326
DOI: 10.1016/j.arcmed.2024.102970

Genes

GEMIN4

Variants

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