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Article

Germline genetic markers for urinary bladder cancer risk, prognosis and treatment response.

Future oncology (London, England) - 1 Sept 2010

Grotenhuis Anne J, Vermeulen Sita H, Kiemeney Lambertus A

Abstract excerpt

After decades of research using a candidate gene approach, only NAT2 and GSTM1 have consistently been demonstrated to be germline genetic susceptibility markers for urinary bladder cancer (UBC). The recent shift to an agnostic genome-wide association approach led to the identification of several UBC susceptibility loci, and provided valuable leads for new mechanistic insights into UBC carcinogenesis. The markers...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 20919828
DOI: 10.2217/fon.10.109

Genes

UBC
GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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