Article
Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer.
Cancer research - 1 Apr 2008
Yang Hushan, Dinney Colin P, Ye Yuanqing, Zhu Yong, Grossman H Barton, Wu Xifeng
Abstract excerpt
MicroRNAs (miRNA) are small noncoding RNA molecules involved in a diversity of cellular functions. Although it has been reported that global suppression of the miRNA biogenesis pathway leads to enhanced tumorigenesis, the effect of common genetic variants of miRNA-related genes on cancer predisposition is unclear. To better understand this effect, we genotyped 41 single-nucleotide polymorphisms (SNP) from 24...
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