Article
Subtype Transdifferentiation in Human Cancer: The Power of Tissue Plasticity in Tumor Progression
17 Feb 2024
Abstract excerpt
The classification of tumors into subtypes, characterized by phenotypes determined by specific differentiation pathways, aids diagnosis and directs therapy towards targeted approaches. However, with the advent and explosion of next-generation sequencing, cancer phenotypes are turning out to be far more heterogenous than initially thought, and the classification is continually being updated to include more...
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