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Isolation of circulating endothelial cells provides tool to determine endothelial cell senescence in blood samples

21 Feb 2024

Abstract excerpt

Circulating endothelial cells (CEC) are arising as biomarkers for vascular diseases. However, whether they can be utilized as markers of endothelial cell (EC) senescence in vivo remains unknown. Here, we present a protocol to isolate circulating endothelial cells for a characterization of their senescent signature. Further, we characterize different models of EC senescence induction in vitro and show similar...

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PMID: 38383692
DOI: 10.1038/s41598-024-54455-5

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