Article
A Two-Sample Mendelian Randomization Analysis Investigates Associations Between Gut Microbiota and Celiac Disease.
Nutrients - 14 May 2020
García-Santisteban Iraia, Cilleros-Portet Ariadna, Moyua-Ormazabal Elisabet, Kurilshikov Alexander, Zhernakova Alexandra, Garcia-Etxebarria Koldo, Fernandez-Jimenez Nora, Bilbao Jose Ramon
Abstract excerpt
Celiac disease (CeD) is a complex immune-mediated inflammatory condition triggered by the ingestion of gluten in genetically predisposed individuals. Literature suggests that alterations in gut microbiota composition and function precede the onset of CeD. Considering that microbiota is partly determined by host genetics, we speculated that the genetic makeup of CeD patients could elicit disease development...
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