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Article

Influence of CYP2D6 Metabolizer Status on Risperidone and Paliperidone Tolerability in Children and Adolescents.

Journal of child and adolescent psychopharmacology - 1 Feb 2024

Kanu Amarachi A, Johnston Michelle M, Poweleit Ethan A, Vaughn Samuel E, Strawn Jeffrey R, Ramsey Laura B

Abstract excerpt

Background: Risperidone and, to a lesser extent, paliperidone are metabolized by CYP2D6; however, there are limited data related to variation in CYP2D6 phenotypes and the tolerability of these medications in children and adolescents. Furthermore, the impact of CYP2D6 on the association of risperidone and paliperidone with hyperprolactinemia in youth is not well understood. Methods: A retrospective chart review...

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Source

Identifiers

PMID: 38377522
DOI: 10.1089/cap.2023.0046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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