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Article

Population pharmacokinetic modeling of risperidone and 9-hydroxyrisperidone to estimate CYP2D6 subpopulations in children and adolescents.

Therapeutic drug monitoring - 1 Oct 2012

Sherwin Catherine M T, Saldaña Shannon N, Bies Robert R, Aman Michael G, Vinks Alexander A

Abstract excerpt

AIM: The study aims were to characterize risperidone and (±)-9-hydroxyrisperidone pharmacokinetic (PK) variability in children and adolescents and to evaluate covariate effects on PK parameters. METHODS: Steady-state samples were drawn at predose, 1, 2, 4, and 7 hours postdose; cytochrome P450 2D...

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Identifiers

PMID: 22929407
DOI: 10.1097/FTD.0b013e318261c240
PMCID: PMC3442132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22929407-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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