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Article

Shared genomic segments analysis identifies MHC class I and class III molecules as genetic risk factors for juvenile idiopathic arthritis.

HGG advances - 11 Apr 2024

Avery Cecile N, Russell Nicole D, Steely Cody J, Hersh Aimee O, Bohnsack John F, Prahalad Sampath, Jorde Lynn B

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is a complex rheumatic disease encompassing several clinically defined subtypes of varying severity. The etiology of JIA remains largely unknown, but genome-wide association studies (GWASs) have identified up to 22 genes associated with JIA susceptibility, including a well-established association with HLA-DRB1. Continued investigation of heritable risk factors has been hindered...

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Share to Arthritis, Juvenile
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38369753
DOI: 10.1016/j.xhgg.2024.100277
PMCID: PMC10918567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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