Article
Whole-Genome Sequencing Analysis of Male Breast Cancer Unveils Novel Structural Events and Potential Therapeutic Targets.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2024
Al Assaad Majd, Michaud Olivier, Semaan Alissa, Sigouros Michael, Tranquille Marvel, Phan Andy, Levine Max F, Gundem Gunes, Medina-Martínez Juan S, Papaemmanuil Elli, Manohar Jyothi, Wilkes David, Sboner Andrea, Hoda Syed A F, Elemento Olivier, Mosquera Juan Miguel
Abstract excerpt
The molecular characterization of male breast cancer (MaBC) has received limited attention in research, mostly because of its low incidence rate, accounting for only 0.5% to 1% of all reported cases of breast cancer each year. Managing MaBC presents significant challenges, with most treatment protocols being adapted from those developed for female breast cancer. Utilizing whole-genome sequencing (WGS) and...
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