Article
High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer.
Breast cancer research and treatment - 1 Oct 2011
Johansson Ida, Nilsson Cecilia, Berglund Pontus, Strand Carina, Jönsson Göran, Staaf Johan, Ringnér Markus, Nevanlinna Heli, Barkardottir Rosa B, Borg Ake, Olsson Håkan, Luts Lena, Fjällskog Marie-Louise, Hedenfalk Ingrid
Abstract excerpt
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characterize MBC by genomic imbalances and to compare it with female breast cancer (FBC), and further to investigate whether the genomic profiles hold any prognostic information. Fifty-six fresh frozen MBC tumors were analyzed using high-resolution tiling BAC arrays....
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