Article
Allele-specific expression analysis reveals conserved and unique features of preimplantation development in equine ICSI embryos†.
Biology of reproduction - 20 Dec 2021
Goszczynski D E, Tinetti P S, Choi Y H, Ross P J, Hinrichs K
Abstract excerpt
Embryonic genome activation and dosage compensation are major genetic events in early development. Combined analysis of single embryo RNA-seq data and parental genome sequencing was used to evaluate parental contributions to early development and investigate X-chromosome dynamics. In addition, we evaluated dimorphism in gene expression between male and female embryos. Evaluation of parent-specific gene expression...
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