Article
Association of Wnt3A gene variants with non-syndromic cleft lip with or without cleft palate in Chinese population.
Archives of oral biology - 1 Jan 2011
Yao Ting, Yang Lan, Li Pei-Qiang, Wu Hua, Xie Han-Bing, Shen Xi, Xie Xiao-Dong
Abstract excerpt
OBJECTIVE: non-syndromic cleft lip with or without cleft palate (NSCLP) is one of the most common birth defects all over the world. Both genetic and environmental factors may contribute to NSCLP. Recent studies have demonstrated that Wnt/β-catenin signalling pathway is required for lip and palate formation. WNT family may play an important role in the development of NSCLP. This study aimed to evaluate the...
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